Radiation as a carcinogen was first established in December 1895 after Roentgen’s discovery of X-rays. In 1902, the first radiation induced cancer was reported emerging from an ulcerated area of the skin. By 1911, a large number of these such skin cancers were reported as well as the first report of leukemia occurring in five radiation workers (Little 2000). Following these discoveries, large-scale tumor induction studies were carried out in animal models over the following 30 years. These studies elucidated many of the general characteristics of radiation carcinogenesis. With the explosion of the atom bomb in Hiroshima and Nagasaki in 1945, scientists were given the opportunity to examine the effects of radiation in a natural experiment th
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