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Human genome project

The Department of Energy and the National Institutes of Health jointly launched a five-year plan to start in fiscal 1991. In essence, this was to be the first leg of a more ambitious series of 3 five-year plans with the ultimate objective that the entire 3 billion bases of a single copy of the human genome would be mapped and sequenced. The first five year proposal, as spelled out in the formal document, was to saturate the genome with markers spaced originally 10 cM apart, meaning about 300 to 400 markers, and, subsequently, at 1cM, necessitating 10 times that number. Thus the entire genome would be "mapped" at equally-spaced and uniquely specific loci. Sequencing, on the other hand, would focus on areas of interest mainly directed to huma

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